Funds from this grant support an effort by a new non-profit, Actuate, led by Arati Prabhakar and Wade Shen, to begin to develop, build, and test “DataSafes,” an end-to-end, multi-party, and privacy-preserving system for sharing, linking, modeling, and analyzing sensitive data. Using advanced mathematical techniques like differential privacy and fully homomorphic encryption, DataSafes will provide a platform where data that would be dangerous to share openly can be analyzed in provably safe, trustworthy, and productive ways. Potential use cases include bankers who want to detect fraud patterns across their industry without identifying their clients, doctors who want to quantify disease spread without identifying their patients, or economists who want to identify poverty causes without identifying tax filers. Grant funds will allow Prabhakar and Shen to begin developing the open-source protocols, prototypes, standards, and code libraries that constitute the foundational technological architecture of the platform. Grant expenditures will be overseen by the Hopewell Fund, a fiscal sponsor for Actuate.