This grant provides support for the production of a six-hour television series, to be produced by documentarian Ken Burns and broadcast on PBS, on the past, present, and future of cancer science. Based on Siddhartha Mukherjee’s Pulitzer Prize-winning bestseller:  The Emperor of All Maladies. The Story of Cancer, the series will offer cinema-veritй style stories about patients and their caregivers and will delve into the latest scientific advances in cancer research, including how the sequencing of the human genome, has transformed  our understanding of the genetic, cellular, and molecular basis of cancer.  The series will focus on three specific types of cancer—leukemia, breast, and lung—in an effort to give a broad overview of the complexity of this disease.